핵분배단백질 누드E 호몰로지 1 은 인간에서 NDE1 유전자 에 의해 암호화된 단백질 이다.[5] [6] [7]
임상적 유의성 NDE1의 양쪽 복사본에서 돌연변이 는 소결핵증 타입 4를 유발한다.[8]
참조 ^ a b c ENSG00000275911 GRCh38: 앙상블 릴리스 89: ENSG000072864, ENSG00000275911 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리스 89: ENSMUSG000022678 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Kitagawa M, Umezu M, Aoki J, Koizumi H, Arai H, Inoue K (Sep 2000). "Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE" . FEBS Lett . 479 (1–2): 57–62. doi :10.1016/S0014-5793(00)01856-1 PMID 10940388 . ^ Meyer G, Perez-Garcia CG, Gleeson JG (Nov 2002). "Selective expression of doublecortin and LIS1 in developing human cortex suggests unique modes of neuronal movement". Cereb Cortex . 12 (12): 1225–36. doi :10.1093/cercor/12.12.1225 . PMID 12427674 . ^ "Entrez Gene: NDE1 nudE nuclear distribution gene E homolog 1 (A. nidulans)" .^ "OMIM Entry - # 614019 - LISSENCEPHALY 4; LIS4" . omim.org . Retrieved 2019-12-10 .
추가 읽기 Feng Y, Olson EC, Stukenberg PT, et al. (2001). "LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome" . Neuron . 28 (3): 665–79. doi :10.1016/S0896-6273(00)00145-8 PMID 11163258 . Türeci O, Sahin U, Koslowski M, et al. (2002). "A novel tumour associated leucine zipper protein targeting to sites of gene transcription and splicing" . Oncogene . 21 (24): 3879–88. doi :10.1038/sj.onc.1205481 PMID 12032826 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Yan X, Li F, Liang Y, et al. (2003). "Human Nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle" . Mol. Cell. Biol . 23 (4): 1239–50. doi :10.1128/MCB.23.4.1239-1250.2003 . PMC 141156 PMID 12556484 . Millar JK, Christie S, Porteous DJ (2004). "Yeast two-hybrid screens implicate DISC1 in brain development and function". Biochem. Biophys. Res. Commun . 311 (4): 1019–25. doi :10.1016/j.bbrc.2003.10.101 . PMID 14623284 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 . Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" . Curr. Biol . 14 (16): 1436–50. doi :10.1016/j.cub.2004.07.051 PMID 15324660 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol . 23 (1): 94–101. doi :10.1038/nbt1046 . PMID 15592455 . S2CID 7200157 . Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16" (PDF) . Nature . 432 (7020): 988–94. doi :10.1038/nature03187 PMID 15616553 . S2CID 4362044 . Brandon NJ, Schurov I, Camargo LM, et al. (2005). "Subcellular targeting of DISC1 is dependent on a domain independent from the Nudel binding site". Mol. Cell. Neurosci . 28 (4): 613–24. doi :10.1016/j.mcn.2004.11.003 . PMID 15797709 . S2CID 28369678 . Guo J, Yang Z, Song W, et al. (2006). "Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly" . Mol. Biol. Cell . 17 (2): 680–9. doi :10.1091/mbc.E05-04-0360 . PMC 1356579 PMID 16291865 . Hirohashi Y, Wang Q, Liu Q, et al. (2006). "Centrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylation" . Oncogene . 25 (45): 6048–55. doi :10.1038/sj.onc.1209637 PMID 16682949 . Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . Hennah W, Tomppo L, Hiekkalinna T, et al. (2007). "Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1" . Hum. Mol. Genet . 16 (5): 453–62. doi :10.1093/hmg/ddl462 PMID 17185386 . 
