MT1E

MT1E
식별자
에일리어스	MT1E, MT1, MTD, MT-1E, MT-IE, 메탈로티오네인 1E
외부 ID	OMIM: 156351 HomoloGene: 138433 GenCard: MT1E
유전자 위치(인간)
크르.	16번 염색체(인간)
끝.	56,627,112 bp
RNA발현패턴
	상단 표시 위치:
	외이성 망막; ; 심막; ; 간우엽; ; 활액관절; ; 내장글로부페리더스; ; 신장세관; ; 좌측 자궁관; ; 갑상선 우엽; ; 후구; ; 갑상선 좌엽;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	아연 이온 결합; 금속 이온 결합;
셀룰러 컴포넌트	세포질; 세포질핵주위영역; 핵;
생물학적 과정	성장의 마이너스 조절; 카드뮴 이온에 대한 세포 반응; 아연 이온에 대한 세포 반응; 세포 아연 이온 항상성; 구리 이온의 해독; 구리 이온에 대한 세포 반응;
	출처:아미고 / QuickGO
맞춤법
	4493
	없음
	ENSG00000169715
	없음
	P04732
	없음
	NM_175617; NM_001363555
	없음
	NP_783316; NP_001350484
	없음
	위키데이터
인간 보기/편집

Metalothionein-1E는 MT1E ^[3]^[4]^[5]유전자에 의해 인간에게 암호화되는 단백질이다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000169715 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB (Oct 1984). "Human metallothionein genes are clustered on chromosome 16". Proc Natl Acad Sci U S A. 81 (17): 5494–8. Bibcode:1984PNAS...81.5494K. doi:10.1073/pnas.81.17.5494. PMC 391732. PMID 6089206.
^ Schmidt CJ, Jubier MF, Hamer DH (Jul 1985). "Structure and expression of two human metallothionein-I isoform genes and a related pseudogene". J Biol Chem. 260 (12): 7731–7. doi:10.1016/S0021-9258(17)39668-0. PMID 2581970.
^ "Entrez Gene: MT1E metallothionein 1E".

추가 정보

West AK, Stallings R, Hildebrand CE, et al. (1991). "Human metallothionein genes: structure of the functional locus at 16q13". Genomics. 8 (3): 513–8. doi:10.1016/0888-7543(90)90038-V. PMID 2286373.
Le Beau MM, Diaz MO, Karin M, Rowley JD (1985). "Metallothionein gene cluster is split by chromosome 16 rearrangements in myelomonocytic leukaemia". Nature. 313 (6004): 709–11. Bibcode:1985Natur.313..709L. doi:10.1038/313709a0. PMID 3856101. S2CID 4321473.
Carter AD, Felber BK, Walling MJ, et al. (1985). "Duplicated heavy metal control sequences of the mouse metallothionein-I gene". Proc. Natl. Acad. Sci. U.S.A. 81 (23): 7392–6. doi:10.1073/pnas.81.23.7392. PMC 392152. PMID 6095291.
Kondo Y, Kuo SM, Lazo JS (1994). "Interleukin-1 beta-mediated metallothionein induction and cytoprotection against cadmium and cis-diamminedichloroplatinum". J. Pharmacol. Exp. Ther. 270 (3): 1313–8. PMID 7932184.
Pauwels M, van Weyenbergh J, Soumillion A, et al. (1994). "Induction by zinc of specific metallothionein isoforms in human monocytes". Eur. J. Biochem. 220 (1): 105–10. doi:10.1111/j.1432-1033.1994.tb18603.x. PMID 8119276.
Vandeghinste N, Proost P, De Ley M (2000). "Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes". Cell. Mol. Biol. (Noisy-le-grand). 46 (2): 419–33. PMID 10774930.
Nguyen A, Jing Z, Mahoney PS, et al. (2000). "In vivo gene expression profile analysis of metallothionein in renal cell carcinoma". Cancer Lett. 160 (2): 133–40. doi:10.1016/S0304-3835(00)00534-6. PMID 11053642.
Oppermann B, Zhang W, Magabo K, Kantorow M (2001). "Identification and spatial analysis of metallothioneins expressed by the adult human lens". Invest. Ophthalmol. Vis. Sci. 42 (1): 188–93. PMC 2957813. PMID 11133866.
Garrett SH, Belcastro M, Sens MA, et al. (2001). "Acute exposure to arsenite induces metallothionein isoform-specific gene expression in human proximal tubule cells". J. Toxicol. Environ. Health A. 64 (4): 343–55. doi:10.1080/152873901316981321. PMID 11693492. S2CID 43143430.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID 12539042. S2CID 26145639.
Hawse JR, Cumming JR, Oppermann B, et al. (2003). "Activation of metallothioneins and alpha-crystallin/sHSPs in human lens epithelial cells by specific metals and the metal content of aging clear human lenses". Invest. Ophthalmol. Vis. Sci. 44 (2): 672–9. doi:10.1167/iovs.02-0018. PMC 2825746. PMID 12556398.
Sens D, Rossi M, Park S, et al. (2003). "Metallothionein isoform 1 and 2 gene expression in a human urothelial cell line (UROtsa) exposed to CdCl2 and NaAsO2". J. Toxicol. Environ. Health A. 66 (21): 2031–46. doi:10.1080/713853980. PMID 14555400.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Sun NN, Fastje CD, Wong SS, et al. (2005). "Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line". Toxicology and Industrial Health. 19 (7–10): 157–63. doi:10.1191/0748233703th185oa. PMID 15747776. S2CID 14394243.
Lederer CW, Torrisi A, Pantelidou M, et al. (2007). "Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis". BMC Genomics. 8: 26. doi:10.1186/1471-2164-8-26. PMC 1796866. PMID 17244347.