테스틸린 또는 PAST1(PAST1 )이라고도 알려진 EH 도메인 함유 단백질 1은 EHD 단백질 패밀리에 속하는 EHD1 [5] 유전자에 의해 인체 내에서 암호화되는 단백질 이다.
기능. 이 유전자는 EPS15 호몰로지(EH) 도메인을 포함한 단백질을 코드하는 고도로 보존된 유전자군에 속한다. 단백질 결합 EH 도메인은 표피 성장인자 수용체용 기질인 EPS15 에서 처음 발견되었다. EH 도메인은 단백질-단백질 상호작용과 세포내 분류에 관여하는 단백질에서 중요한 모티브로 나타났다. 이 유전자에 의해 코드된 단백질은 IGF1 [5] 수용체의 세포내구증에서 역할을 하는 것으로 생각된다.
상호 작용 EHD1은 인슐린 유사 성장인자 1 [6] 수용체 및 SNAP29 와 [6] 상호작용하는 것 으로 나타났다.
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