BDP1 식별자 에일리어스 BDP1 , HSA238520, TAF3B1, TFC5, TFIIIB150, TFIIIB90, TFNR, B 더블프라임1, RNA 중합효소III 전사개시인자 IIIB 서브유닛, DFNB112, TFIIIB'외부 ID OMIM : 607012 MGI : 1347077 HomoloGene : 34582 GenCard : BDP1 맞춤법 종. 인간 마우스 엔트레즈 앙상블 유니프로트 RefSeq(mRNA) RefSeq(단백질) 장소(UCSC) Chr 5: 71.46 ~71.57 Mb Chr 13: 100.02 ~100.1 Mb PubMed 검색[3] [4] 위키데이터
TFIIIB150이라고 도 불리는 전사인자 TFIIB 성분 B' 상동물은 BDP1 [5] [6] [7] 유전자에 의해 인체에서 코드되는 단백질 이다.
기능. TFIIIB150은 TFIIB 전사 개시 복합체의 서브유닛으로 전사를 개시하기 위해 RNA 중합효소 III를 표적 프로모터로 모집한다. 암호화된 단백질은 핵의 농축된 응집물에 국소화되며, 세 가지 유형의 중합효소 III 촉진제 모두의 전사에 필요합니다. 유사분열 중에 카제인 키나제 2에 의해 인산화되어 염색질 에서 방출되고 중합효소 III [7] 전사가 억제된다.
레퍼런스 ^ a b c ENSG00000273873, ENSG00000145734 GRCh38: Ensembl 릴리즈 89: ENSG00000274803, ENSG00000273873, ENSG00000145734 : Ensembl , 2017년 5월 ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000049658 - 앙상블 , 2017년 5월 ^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine . ^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Res . 7 (6): 347–55. doi :10.1093/dnares/7.6.347 . PMID 11214970 . ^ Schramm L, Pendergrast PS, Sun Y, Hernandez N (Nov 2000). "Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters" . Genes Dev . 14 (20): 2650–63. doi :10.1101/gad.836400 . PMC 316990 . PMID 11040218 . ^ a b "Entrez Gene: BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB" .
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