호모 사피엔스 종의 단백질 코드 유전자
BAG 패밀리 분자 샤페론 조절기 2는 BAG2 [5] [6] 단백질 이다.
BAG 단백질은 Hsc70/Hsp70 ATPase 도메인에 결합하기 위해 Hip과 경쟁하고 기질 방출을 촉진합니다. 모든 BAG 단백질은 C 말단 부근에 약 45-아미노산 BAG 도메인 을 가지지만 N 말단 영역에서는 현저하게 다르다. 예측된 BAG2 단백질은 211개의 아미노산을 함유하고 있다. BAG1, BAG2, BAG3의 BAG 도메인은 체외 및 포유류 세포에서 Hsc70 ATPase 도메인과 특이하게 상호작용한다. 3가지 단백질 모두 Hsc70의 ATP효소 도메인에 높은 친화력으로 결합하고 Hip-repressible 방식으로 [6]
상호 작용 BAG2는 HSPA8 과 [5] 것 으로 나타났습니다.
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