유비퀴틴 D

UBD
사용 가능한 구조
PDB	Ortholog 검색: PDBe RCSB
PDB ID 코드 목록
	2 MBE
식별자
에일리어스	UBD, FAT10, GABR1, UBD-3, 유비퀴틴D
외부 ID	OMIM: 606050 MGI: 1344410 HomoloGene: 4665 GeneCard: UBD
유전자 위치(인간)
크르.	6번 염색체(인간)
끝.	29,559,732 bp
유전자 위치(마우스)
크르.	17번 염색체(쥐)
끝.	37,506,986 bp
RNA발현패턴
	상단 표시 위치:
	부록; ; 림프절; ; 랑게르한스 섬; ; 직장; ; 담낭; ; 신장; ; 흉선; ; 간; ; 비장; ; 췌장체;
	추가 참조 표현식 데이터
	없음
유전자 존재론
분자 함수	프로테아솜 결합; GO:0001948 단백질 결합;
셀룰러 컴포넌트	세포질; 귀찮다; 핵; 섬유 중심; 세포;
생물학적 과정	I-kappaB인산화효소/NF-kappaB신호의 양성조절; 종양괴사인자에 대한 반응; 골수 수상세포 분화; 소단백질 결합에 의한 단백질 수식; 단백질유비퀴티네이션; 유비퀴틴의존성 단백질 이화 과정; 인터페론의 매개에 의한 반응; 단백질 분해; 귀찮은 조립; 아포토시스 과정의 양성 조절; 발육 후 단백질 수식; 유사분열세포주기상전이조절;
	출처:아미고 / QuickGO
맞춤법
	10537
	24108
ENSG00000228913; ENSG00000231968; ENSG00000206468; ENSG00000206513; ENSG00000224654;
	ENSG00000213886; ENSG00000226898
	ENSMUSG000035186
	O15205
	P63072
	NM_006398
	NM_023137
	NP_006389
	NP_075626
	위키데이터
인간 보기/편집	마우스 표시/편집

유비퀴틴 D는 인간의 UBD ^[5]^[6]^[7]유전자에 의해 암호화되는 단백질이다.

상호 작용

UBD(gene)는 NUB1^[8] 및 MAD2L1과 ^[9]상호 작용하는 것으로 나타났습니다.

레퍼런스

^ ^a ^b ^c ENSG00000231968, ENSG00000206468, ENSG00000206513, ENSG00000224654, ENSG00000213886, ENSG000002268 GRCh38: Ensubl 릴리즈 89: ENSG00000228913, ENSG000001968, ENSG
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000035186 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bates EE, Ravel O, Dieu MC, Ho S, Guret C, Bridon JM, Ait-Yahia S, Brière F, Caux C, Banchereau J, Lebecque S (Oct 1997). "Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells". European Journal of Immunology. 27 (10): 2471–7. doi:10.1002/eji.1830271002. PMID 9368598. S2CID 21652482.
^ Fan W, Cai W, Parimoo S, Schwarz DC, Lennon GG, Weissman SM (Aug 1996). "Identification of seven new human MHC class I region genes around the HLA-F locus". Immunogenetics. 44 (2): 97–103. doi:10.1007/BF02660056. PMID 8662070. S2CID 21628804.
^ "Entrez Gene: UBD ubiquitin D".
^ Hipp MS, Raasi S, Groettrup M, Schmidtke G (Apr 2004). "NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation". The Journal of Biological Chemistry. 279 (16): 16503–10. doi:10.1074/jbc.M310114200. PMID 14757770.
^ Liu YC, Pan J, Zhang C, Fan W, Collinge M, Bender JR, Weissman SM (Apr 1999). "A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2". Proceedings of the National Academy of Sciences of the United States of America. 96 (8): 4313–8. Bibcode:1999PNAS...96.4313L. doi:10.1073/pnas.96.8.4313. PMC 16329. PMID 10200259.

추가 정보

Mazzé FM, Degrève L (2006). "The role of viral and cellular proteins in the budding of human immunodeficiency virus". Acta Virologica. 50 (2): 75–85. PMID 16808324.
Ott DE, Coren LV, Copeland TD, Kane BP, Johnson DG, Sowder RC, Yoshinaka Y, Oroszlan S, Arthur LO, Henderson LE (Apr 1998). "Ubiquitin is covalently attached to the p6Gag proteins of human immunodeficiency virus type 1 and simian immunodeficiency virus and to the p12Gag protein of Moloney murine leukemia virus". Journal of Virology. 72 (4): 2962–8. doi:10.1128/JVI.72.4.2962-2968.1998. PMC 109742. PMID 9525617.
Liu YC, Pan J, Zhang C, Fan W, Collinge M, Bender JR, Weissman SM (Apr 1999). "A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2". Proceedings of the National Academy of Sciences of the United States of America. 96 (8): 4313–8. Bibcode:1999PNAS...96.4313L. doi:10.1073/pnas.96.8.4313. PMC 16329. PMID 10200259.
Schubert U, Ott DE, Chertova EN, Welker R, Tessmer U, Princiotta MF, Bennink JR, Krausslich HG, Yewdell JW (Nov 2000). "Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2". Proceedings of the National Academy of Sciences of the United States of America. 97 (24): 13057–62. Bibcode:2000PNAS...9713057S. doi:10.1073/pnas.97.24.13057. PMC 27177. PMID 11087859.
Strack B, Calistri A, Accola MA, Palu G, Gottlinger HG (Nov 2000). "A role for ubiquitin ligase recruitment in retrovirus release". Proceedings of the National Academy of Sciences of the United States of America. 97 (24): 13063–8. Bibcode:2000PNAS...9713063S. doi:10.1073/pnas.97.24.13063. PMC 27178. PMID 11087860.
Ott DE, Coren LV, Chertova EN, Gagliardi TD, Schubert U (Dec 2000). "Ubiquitination of HIV-1 and MuLV Gag". Virology. 278 (1): 111–21. doi:10.1006/viro.2000.0648. PMID 11112487.
Strack B, Calistri A, Göttlinger HG (Jun 2002). "Late assembly domain function can exhibit context dependence and involves ubiquitin residues implicated in endocytosis". Journal of Virology. 76 (11): 5472–9. doi:10.1128/JVI.76.11.5472-5479.2002. PMC 137019. PMID 11991975.
Ott DE, Coren LV, Sowder RC, Adams J, Schubert U (Mar 2003). "Retroviruses have differing requirements for proteasome function in the budding process". Journal of Virology. 77 (6): 3384–93. doi:10.1128/JVI.77.6.3384-3393.2003. PMC 149504. PMID 12610113.
Lee CG, Ren J, Cheong IS, Ban KH, Ooi LL, Yong Tan S, Kan A, Nuchprayoon I, Jin R, Lee KH, Choti M, Lee LA (May 2003). "Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers". Oncogene. 22 (17): 2592–603. doi:10.1038/sj.onc.1206337. PMID 12730673.
Brès V, Kiernan RE, Linares LK, Chable-Bessia C, Plechakova O, Tréand C, Emiliani S, Peloponese JM, Jeang KT, Coux O, Scheffner M, Benkirane M (Aug 2003). "A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter". Nature Cell Biology. 5 (8): 754–61. doi:10.1038/ncb1023. PMID 12883554. S2CID 8414608.
Hipp MS, Raasi S, Groettrup M, Schmidtke G (Apr 2004). "NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation". The Journal of Biological Chemistry. 279 (16): 16503–10. doi:10.1074/jbc.M310114200. PMID 14757770.
Barrios-Rodiles M, Brown KR, Ozdamar B, Bose R, Liu Z, Donovan RS, Shinjo F, Liu Y, Dembowy J, Taylor IW, Luga V, Przulj N, Robinson M, Suzuki H, Hayashizaki Y, Jurisica I, Wrana JL (Mar 2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. Bibcode:2005Sci...307.1621B. doi:10.1126/science.1105776. PMID 15761153. S2CID 39457788.
Hipp MS, Kalveram B, Raasi S, Groettrup M, Schmidtke G (May 2005). "FAT10, a ubiquitin-independent signal for proteasomal degradation". Molecular and Cellular Biology. 25 (9): 3483–91. doi:10.1128/MCB.25.9.3483-3491.2005. PMC 1084302. PMID 15831455.
Gottwein E, Kräusslich HG (Jul 2005). "Analysis of human immunodeficiency virus type 1 Gag ubiquitination". Journal of Virology. 79 (14): 9134–44. doi:10.1128/JVI.79.14.9134-9144.2005. PMC 1168789. PMID 15994808.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

이 단백질 관련 기사는 스텁입니다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] ENSG00000231968, ENSG00000206468, ENSG00000206513, ENSG00000224654, ENSG00000213886, ENSG000002268 GRCh38: Ensubl 릴리즈 89: ENSG00000228913, ENSG000001968, ENSG

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000035186 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9368598-5] Bates EE, Ravel O, Dieu MC, Ho S, Guret C, Bridon JM, Ait-Yahia S, Brière F, Caux C, Banchereau J, Lebecque S (Oct 1997). "Identification and analysis of a novel member of the ubiquitin family expressed in dendritic cells and mature B cells". European Journal of Immunology. 27 (10): 2471–7. doi:10.1002/eji.1830271002. PMID 9368598. S2CID 21652482.

[pmid8662070-6] Fan W, Cai W, Parimoo S, Schwarz DC, Lennon GG, Weissman SM (Aug 1996). "Identification of seven new human MHC class I region genes around the HLA-F locus". Immunogenetics. 44 (2): 97–103. doi:10.1007/BF02660056. PMID 8662070. S2CID 21628804.

[entrez-7] "Entrez Gene: UBD ubiquitin D".

[pmid14757770-8] Hipp MS, Raasi S, Groettrup M, Schmidtke G (Apr 2004). "NEDD8 ultimate buster-1L interacts with the ubiquitin-like protein FAT10 and accelerates its degradation". The Journal of Biological Chemistry. 279 (16): 16503–10. doi:10.1074/jbc.M310114200. PMID 14757770.

[pmid10200259-9] Liu YC, Pan J, Zhang C, Fan W, Collinge M, Bender JR, Weissman SM (Apr 1999). "A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2". Proceedings of the National Academy of Sciences of the United States of America. 96 (8): 4313–8. Bibcode:1999PNAS...96.4313L. doi:10.1073/pnas.96.8.4313. PMC 16329. PMID 10200259.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

Search

유비퀴틴 D

네임스페이스

더

상호 작용

레퍼런스

추가 정보