세르비아P1

세르비아P1
사용 가능한 구조
PDB	Ortholog 검색: PDBe RCSB
PDB ID 코드 목록
	4V6X
식별자
에일리어스	SERVP1, CHD3IP, HABP4L, PAI-RBP1, PAREBP1, CGI-55, SERPINE1 mRNA결합단백질 1
외부 ID	OMIM: 607378 MGI: 1914120 HomoloGene: 134277 GenCard: SERVP1
유전자 위치(인간)
크르.	1번 염색체(인간)
끝.	67,415 bp
유전자 위치(마우스)
크르.	6번 염색체(쥐)
끝.	67,274,194 bp
RNA발현패턴
	상단 표시 위치:
	아킬레스건; ; 결석골; ; 두정 흉막; ; 외음부; ; 상완 삼두근; ; 잇몸; ; 구강; ; 경골; ; 내장 흉막; ; 태아;
	상단 표시 위치:
	원시적 특징; ; 복벽; ; 콘딜; ; 수채관; ; 모낭; ; 신장 소체; ; 광학 플래코드; ; 밧세루; ; 혈관 형성; ; 내경동맥;
	추가 참조 표현식 데이터
	; ; ; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	단백질 결합; mRNA3'-UTR결합; RNA결합; 카드헤린 결합; 스모 바인딩;
셀룰러 컴포넌트	세포질핵주위영역; 혈장막; 세포외 엑소좀; 막; 세포; 핵; 세포질;
생물학적 과정	아포토시스 과정 조절; mRNA 안정성 조절; PML 바디 구성;
	출처:아미고 / QuickGO
맞춤법
	26135
	66870
	ENSG00000142864
	ENSMUSG000036371
	Q8NC51
	Q9CY58
	NM_015640; NM_001018067; NM_001018068; NM_001018069
	NM_001113564; NM_001113565; NM_001113566; NM_025814
	NP_001018077; NP_001018078; NP_001018079; NP_056455
	NP_001107036; NP_001107037; NP_001107038; NP_080090
	위키데이터
인간 보기/편집	마우스 표시/편집

플라스미노겐활성화억제제 1 RNA결합단백질(serbp1)은 SERVP1 ^[5]^[6]^[7]유전자에 의해 인체 내에서 암호화되는 단백질이다.

상호 작용

SERVP1은 CHD3와 ^[8]^[9]상호작용하는 것으로 나타났습니다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000142864 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000036371 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Heaton JH, Dlakic WM, Dlakic M, Gelehrter TD (May 2001). "Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA". J Biol Chem. 276 (5): 3341–7. doi:10.1074/jbc.M006538200. PMID 11001948.
^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
^ "Entrez Gene: SERBP1 SERPINE1 mRNA binding protein 1".
^ Lemos TA, Passos DO, Nery FC, Kobarg J (Jan 2003). "Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3". FEBS Lett. Netherlands. 533 (1–3): 14–20. doi:10.1016/S0014-5793(02)03737-7. ISSN 0014-5793. PMID 12505151.
^ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. United States. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. ISSN 0092-8674. PMID 16169070. S2CID 8235923.

추가 정보

Maruyama K; Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Bucková D; Izakovicová Hollá L; Vácha J (2002). "Polymorphism 4G/5G in the plasminogen activator inhibitor-1 (PAI-1) gene is associated with IgE-mediated allergic diseases and asthma in the Czech population". Allergy. 57 (5): 446–8. doi:10.1034/j.1398-9995.2002.03582.x. PMID 11972486. S2CID 23925569.
Jones K, Powell J, Brown L, et al. (2002). "The influence of 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene promoter on the incidence, growth and operative risk of abdominal aortic aneurysm". European Journal of Vascular and Endovascular Surgery. 23 (5): 421–5. doi:10.1053/ejvs.2002.1633. PMID 12027469.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Lemos TA; Passos DO; Nery FC; Kobarg J (2003). "Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3". FEBS Lett. 533 (1–3): 14–20. doi:10.1016/S0014-5793(02)03737-7. PMID 12505151.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Lemos TA; Kobarg J (2006). "CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus". Cell Biochem. Biophys. 44 (3): 463–74. doi:10.1385/CBB:44:3:463. PMID 16679534. S2CID 24544907.
Passos DO; Bressan GC; Nery FC; Kobarg J (2006). "Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation". FEBS J. 273 (17): 3946–61. doi:10.1111/j.1742-4658.2006.05399.x. PMID 16879614.
Dalmáz CA, Santos KG, Botton MR, et al. (2006). "Relationship between polymorphisms in thrombophilic genes and preeclampsia in a Brazilian population". Blood Cells Mol. Dis. 37 (2): 107–10. doi:10.1016/j.bcmd.2006.07.005. PMID 16963292.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

외부 링크

PDB의 UniProt: Q8NC51(플라스미노겐 활성제 억제제 1 RNA 결합 단백질)에서 PDB에서 사용 가능한 모든 구조 정보의 개요.

인간 염색체 1번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000142864 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000036371 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11001948-5] Heaton JH, Dlakic WM, Dlakic M, Gelehrter TD (May 2001). "Identification and cDNA cloning of a novel RNA-binding protein that interacts with the cyclic nucleotide-responsive sequence in the Type-1 plasminogen activator inhibitor mRNA". J Biol Chem. 276 (5): 3341–7. doi:10.1074/jbc.M006538200. PMID 11001948.

[pmid10810093-6] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.

[entrez-7] "Entrez Gene: SERBP1 SERPINE1 mRNA binding protein 1".

[pmid12505151-8] Lemos TA, Passos DO, Nery FC, Kobarg J (Jan 2003). "Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3". FEBS Lett. Netherlands. 533 (1–3): 14–20. doi:10.1016/S0014-5793(02)03737-7. ISSN 0014-5793. PMID 12505151.

[pmid16169070-9] Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. United States. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. ISSN 0092-8674. PMID 16169070. S2CID 8235923.

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세르비아P1

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레퍼런스

추가 정보

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