핵 프리 mRNA에서 인트론 제거는 4개의 작은 핵 리보뉴클레오프로틴(snRNP) 입자와 일시적으로 연관되지 않은 다수의 스플리싱 인자로 구성된 스플리소솜이라는 콤플렉스에서 발생한다.PRPF3는 U4 및 U6 snRNP와 관련된 여러 단백질 중 하나이다.[OMIM에 의해 제공][5]
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