PPIP5K2
PPIP5K2
디포스포이노시톨펜타키스인산인산화효소2는 사람에서 PPIP5K2 유전자에 의해 암호화되는 단백질이다.[5]
기능.
이노시톨 인산염(IPs)과 디포스포이노시톨 인산염(PP-IPs)은 세포 신호 분자로도 알려져 있다.
HISPPD1은 각각 고에너지 피로인산 PP-IP5 및 PP2-IP4(IP8이라고도 함)를 생성하는 IP6 키나제(EC 2.7.4.21)와 PP-IP5 키나제(EC 2.7.4.24) 활성을 가지고 있다(Fridy Et Almed, 2007).
레퍼런스
- ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000145725 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000040648 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Diphosphoinositol pentakisphosphate kinase 2". Retrieved 2017-03-21.
추가 정보
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Wang H, Falck JR, Hall TM, Shears SB (2011). "Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding". Nat. Chem. Biol. 8 (1): 111–6. doi:10.1038/nchembio.733. PMC 3923263. PMID 22119861.
- Weaver JD, Wang H, Shears SB (2013). "The kinetic properties of a human PPIP5K reveal that its kinase activities are protected against the consequences of a deteriorating cellular bioenergetic environment". Biosci. Rep. 33 (2): e00022. doi:10.1042/BSR20120115. PMC 3564036. PMID 23240582.
- Yong ST, Nguyen HN, Choi JH, Bortner CD, Williams J, Pulloor NK, Krishnan MN, Shears SB (2015). "Identification of a functional nuclear translocation sequence in hPPIP5K2". BMC Cell Biol. 16: 17. doi:10.1186/s12860-015-0063-7. PMC 4472268. PMID 26084399.
