PLA2R1

PLA2R1
PLA2R1
식별자
에일리어스PLA2R1, CLEC13C, PLA2-R, PLA2G1R, PLA2IR, PLA2R, 포스포리파아제A2수용체1
외부 IDOMIM: 604939 MGI: 102468 HomoloGene: 32016 GenCards: PLA2R1
맞춤법
종.인간마우스
엔트레즈

22925

18779

앙상블

ENSG00000153246

ENSMUSG000054580

유니프로트

Q13018

Q62028

RefSeq(mRNA)

NM_001007267
NM_001195641
NM_007366

NM_008867

RefSeq(단백질)

NP_001007268
NP_001182570
NP_03139

NP_032893

장소(UCSC)Chr 2: 159.93 ~160.06 MbChr 2: 60.25 ~60.38 Mb
PubMed 검색[3][4]
위키데이터
인간 보기/편집마우스 표시/편집

분비성 포스포리파아제 A2 수용체는 사람에게서 PLA2R1 유전자에 [5][6][7]의해 암호화되는 단백질이다.

임상적 의의

M형 포스포리파아제 A2 수용체는 [8]특발성 막신증의 주요 항원으로 70% 이상이 원인이다.

레퍼런스

  1. ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000153246 - 앙상블, 2017년 5월
  2. ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000054580 - 앙상블, 2017년 5월
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ancian P, Lambeau G, Mattéi MG, Lazdunski M (Apr 1995). "The human 180-kDa receptor for secretory phospholipases A2. Molecular cloning, identification of a secreted soluble form, expression, and chromosomal localization". The Journal of Biological Chemistry. 270 (15): 8963–70. doi:10.1074/jbc.270.15.8963. PMID 7721806.
  6. ^ Higashino K, Ishizaki J, Kishino J, Ohara O, Arita H (Oct 1994). "Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals". European Journal of Biochemistry. 225 (1): 375–82. doi:10.1111/j.1432-1033.1994.00375.x. PMID 7925459.
  7. ^ "Entrez Gene: PLA2R1 phospholipase A2 receptor 1, 180kDa".
  8. ^ Beck LH, Bonegio RG, Lambeau G, Beck DM, Powell DW, Cummins TD, Klein JB, Salant DJ (Jul 2009). "M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy". The New England Journal of Medicine. 361 (1): 11–21. doi:10.1056/NEJMoa0810457. PMC 2762083. PMID 19571279.

추가 정보

  • Silliman CC, Moore EE, Zallen G, Gonzalez R, Johnson JL, Elzi DJ, Meng X, Hanasaki K, Ishizaki J, Arita H, Ao L, England KM, Banerjee A (Oct 2002). "Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion". American Journal of Physiology. Cell Physiology. 283 (4): C1102–13. doi:10.1152/ajpcell.00608.2001. PMID 12225974.
  • Wistow G, Bernstein SL, Wyatt MK, Ray S, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K (Jun 2002). "Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts". Molecular Vision. 8: 196–204. PMID 12107411.
  • Morioka Y, Saiga A, Yokota Y, Suzuki N, Ikeda M, Ono T, Nakano K, Fujii N, Ishizaki J, Arita H, Hanasaki K (Sep 2000). "Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor". Archives of Biochemistry and Biophysics. 381 (1): 31–42. doi:10.1006/abbi.2000.1977. PMID 11019817.
  • Yokota Y, Higashino K, Nakano K, Arita H, Hanasaki K (Jul 2000). "Identification of group X secretory phospholipase A(2) as a natural ligand for mouse phospholipase A(2) receptor". FEBS Letters. 478 (1–2): 187–91. doi:10.1016/S0014-5793(00)01848-2. PMID 10922494. S2CID 28188560.
  • Yokota Y, Ikeda M, Higashino K, Nakano K, Fujii N, Arita H, Hanasaki K (Jul 2000). "Enhanced tissue expression and elevated circulating level of phospholipase A(2) receptor during murine endotoxic shock". Archives of Biochemistry and Biophysics. 379 (1): 7–17. doi:10.1006/abbi.2000.1849. PMID 10864436.
  • Dias Neto E, Correa RG, Verjovski-Almeida S, Briones MR, Nagai MA, da Silva W, Zago MA, Bordin S, Costa FF, Goldman GH, Carvalho AF, Matsukuma A, Baia GS, Simpson DH, Brunstein A, de Oliveira PS, Bucher P, Jongeneel CV, O'Hare MJ, Soares F, Brentani RR, Reis LF, de Souza SJ, Simpson AJ (Mar 2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proceedings of the National Academy of Sciences of the United States of America. 97 (7): 3491–6. doi:10.1073/pnas.97.7.3491. PMC 16267. PMID 10737800.


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인간 염색체 2번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.