LIN9

LIN9
식별자
에일리어스	LIN9, BARA, BARPsv, Lin-9, TGS, TGS1, TGS2, lin-9 DREAM MuvB 코어 복합 컴포넌트
외부 ID	OMIM: 609375 MGI: 1919818 HomoloGene: 35252 GeneCard: LIN9
유전자 위치(인간)
크르.	1번 염색체(인간)
끝.	226,309,869 bp
유전자 위치(마우스)
크르.	1번 염색체(마우스)
끝.	180,518,259 bp
RNA발현패턴
	상단 표시 위치:
	신경절 융기; ; 좌심실; ; 이차 난모세포; ; 우심실; ; 아킬레스건; ; 직장; ; 평활근 조직; ; 자궁내막간질세포; ; 고나드; ; 고환;
	추가 참조 표현식 데이터
	없음
유전자 존재론
분자 함수	GO:0001948 단백질 결합; DNA결합;
셀룰러 컴포넌트	전사억제복합체; 핵; 핵소체;
생물학적 과정	세포 주기; DNA생합성과정; 전사, DNA 템플릿; 세포주기조절; 복제품;
	출처:아미고 / QuickGO
맞춤법
	286826
	72568
	ENSG00000183814
	ENSMUSG000058729
	Q5TKA1
	Q8C735
NM_001270409; NM_001270410; NM_173083; NM_001366237; NM_001366238;
	NM_001366239; NM_001366240; NM_001366241; NM_001366245
	NM_001103182; NM_175186
NP_001257338; NP_001257339; NP_775106; NP_001353166; NP_001353167;
	NP_001353168; NP_001353169; NP_001353170; NP_001353174
	없음
	위키데이터
인간 보기/편집	마우스 표시/편집

Lin-9 호몰로지는 인간의 ^[5]^[6]LIN9 유전자에 의해 암호화되는 단백질이다.

상호 작용

LIN9은 망막아세포종 ^[5]단백질과 상호작용하는 것으로 나타났다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000183814 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000058729 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Gagrica S, Hauser S, Kolfschoten I, Osterloh L, Agami R, Gaubatz S (Nov 2004). "Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein". The EMBO Journal. 23 (23): 4627–38. doi:10.1038/sj.emboj.7600470. PMC 533054. PMID 15538385.
^ "Entrez Gene: LIN9 lin-9 homolog (C. elegans)".

추가 정보

Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Korenjak M, Taylor-Harding B, Binné UK, Satterlee JS, Stevaux O, Aasland R, White-Cooper H, Dyson N, Brehm A (Oct 2004). "Native E2F/RBF complexes contain Myb-interacting proteins and repress transcription of developmentally controlled E2F target genes". Cell. 119 (2): 181–93. doi:10.1016/j.cell.2004.09.034. PMID 15479636.
Sandoval R, Xue J, Tian X, Barrett K, Pilkinton M, Ucker DS, Raychaudhuri P, Kineman RD, Luque RM, Baida G, Zou X, Valli VE, Cook JL, Kiyokawa H, Colamonici OR (Aug 2006). "A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes". Experimental Cell Research. 312 (13): 2465–75. doi:10.1016/j.yexcr.2006.04.002. PMID 16730350.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Pilkinton M, Sandoval R, Song J, Ness SA, Colamonici OR (Jan 2007). "Mip/LIN-9 regulates the expression of B-Myb and the induction of cyclin A, cyclin B, and CDK1". The Journal of Biological Chemistry. 282 (1): 168–75. doi:10.1074/jbc.M609924200. PMID 17098733.
Osterloh L, von Eyss B, Schmit F, Rein L, Hübner D, Samans B, Hauser S, Gaubatz S (Jan 2007). "The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis". The EMBO Journal. 26 (1): 144–57. doi:10.1038/sj.emboj.7601478. PMC 1782375. PMID 17159899.
Pilkinton M, Sandoval R, Colamonici OR (Nov 2007). "Mammalian Mip/LIN-9 interacts with either the p107, p130/E2F4 repressor complex or B-Myb in a cell cycle-phase-dependent context distinct from the Drosophila dREAM complex". Oncogene. 26 (54): 7535–43. doi:10.1038/sj.onc.1210562. PMID 17563750.

인간 염색체 1번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000183814 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000058729 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15538385-5] Gagrica S, Hauser S, Kolfschoten I, Osterloh L, Agami R, Gaubatz S (Nov 2004). "Inhibition of oncogenic transformation by mammalian Lin-9, a pRB-associated protein". The EMBO Journal. 23 (23): 4627–38. doi:10.1038/sj.emboj.7600470. PMC 533054. PMID 15538385.

[entrez-6] "Entrez Gene: LIN9 lin-9 homolog (C. elegans)".

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LIN9

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