헤파 란 황산 글루코사민 3-O-술포전달효소 2는 인체에서 HS3 에 의해 암호화되는 효소 이다.ST2 [5] [6] 유전자
헤파란 황산염 생합성 효소는 여러 생물학적 활성을 수행하는 무수한 별개의 헤파란 황산염 미세 구조를 생성하는 데 중요한 성분이다. 이 유전자에 의해 코드된 효소는 헤파란 황산염 생합성 효소군의 구성원이다. II형 일체막 단백질로 헤파란황산글루코사미닐 3-O-술포전달효소 활성을 가진다. 이 유전자는 주로 뇌에서 발현되며 신경계에서 [6]
유방암에서의 역할 HS3ST2 프로모터는 유방암 조직에서 정상 유방 도관에 비해 과메틸화되어 있어 질병의 [7] 기능 분석 결과 HS3의 상향 조정은 인간 유방암 세포의 ST2는 미토겐 활성화 단백질 키나아제 시그널링과 매트릭스 메탈로프로테이나아제 [8]
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