카프린-1

Caprin-1
캡린 1
사용 가능한 구조
PDBOrtholog 검색: PDBe RCSB
식별자
에일리어스CAPRIN1, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI, 세포주기 관련 단백질 1
외부 IDOMIM: 601178MGI: 1858234 HomoloGene: 4310 GenCards: CAPRIN1
맞춤법
종.인간마우스
엔트레즈
앙상블
유니프로트
RefSeq(mRNA)

NM_005898
NM_203364

NM_001111289
NM_001111290
NM_001111291
NM_001111292
NM_016739

RefSeq(단백질)

NP_005889
NP_976240

NP_001104759
NP_001104760
NP_001104761
NP_001104762
NP_058019

장소(UCSC)Chr 11: 34.05 ~34.1 MbChr 2: 103.59 ~103.63 Mb
PubMed 검색[3][4]
위키데이터
인간 보기/편집마우스 표시/편집

카프린-1CAPRIN1 [5][6][7][8][9][10]유전자에 의해 인간에게 암호화되는 단백질이다.장기기억 [11]형성에 필수적인 것은 Caprin1(a.k.a.RNG105)이다.

레퍼런스

  1. ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000135387 - 앙상블, 2017년 5월
  2. ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000027184 - 앙상블, 2017년 5월
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ellis JA, Luzio JP (September 1995). "Identification and characterization of a novel protein (p137) which transcytoses bidirectionally in Caco-2 cells". The Journal of Biological Chemistry. 270 (35): 20717–23. doi:10.1074/jbc.270.35.20717. PMID 7657653.
  6. ^ Wang B, David MD, Schrader JW (October 2005). "Absence of caprin-1 results in defects in cellular proliferation". Journal of Immunology. 175 (7): 4274–82. doi:10.4049/jimmunol.175.7.4274. PMID 16177067.
  7. ^ Solomon S, Xu Y, Wang B, David MD, Schubert P, Kennedy D, Schrader JW (March 2007). "Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs". Molecular and Cellular Biology. 27 (6): 2324–42. doi:10.1128/MCB.02300-06. PMC 1820512. PMID 17210633.
  8. ^ Grill B, Wilson GM, Zhang KX, Wang B, Doyonnas R, Quadroni M, Schrader JW (February 2004). "Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins". Journal of Immunology. 172 (4): 2389–400. doi:10.4049/jimmunol.172.4.2389. PMID 14764709.
  9. ^ Katsafanas GC, Moss B (December 2004). "Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic activation/proliferation-associated protein (p137) individually or as a heterodimer". The Journal of Biological Chemistry. 279 (50): 52210–7. doi:10.1074/jbc.M411033200. PMID 15471883.
  10. ^ "Entrez Gene: GPIAP1 GPI-anchored membrane protein 1".
  11. ^ Nakayama K, Ohashi R, Shinoda Y, Yamazaki M, Abe M, Fujikawa A, et al. (November 2017). "RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation". eLife. 6. doi:10.7554/eLife.29677. PMC 5697933. PMID 29157358.

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