단백질
텔로미어 관련 단백질 RIF1은 인간 에서 RIF1 유전자에 [5] [6] [7] 단백질 이다.
RIF1과 RIF2 는 [8] 고등 진핵생물에서 Rif1은 DNA 손상 반응, 염색질 구조 구성 및 복제 시기 조절에 관여한다. RIF1은 [9]
레퍼런스 ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG000080345 - 앙상블 , 2017년 5월^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000036202 - 앙상블 , 2017년 5월^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Silverman J, Takai H, Buonomo SB, Eisenhaber F, de Lange T (September 2004). "Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint" . Genes & Development . 18 (17): 2108–19. doi :10.1101/gad.1216004 . PMC 515289 PMID 15342490 . ^ Adams IR, McLaren A (April 2004). "Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells" . Developmental Dynamics . 229 (4): 733–44. doi :10.1002/dvdy.10471 PMID 15042697 . S2CID 22138565 . ^ "Entrez Gene: RIF1 RAP1 interacting factor homolog (yeast)" .^ Ribeyre C, Shore D (2012). "Anticheckpoint pathways at telomeres in yeast". Nature Structural & Molecular Biology . 19 (3): 307–13. doi :10.1038/nsmb.2225 . PMID 22343724 . S2CID 10636976 . ^ Conrad T, Albrecht AS, de Melo Costa VR, Sauer S, Meierhofer D, Ørom UA (2016-01-01). "Serial interactome capture of the human cell nucleus" . Nature Communications . 7 : 11212. Bibcode :2016NatCo...711212C . doi :10.1038/ncomms11212 . PMC 4822031 PMID 27040163 . 추가 정보 Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (April 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry . 236 (1): 107–13. doi :10.1006/abio.1996.0138 . PMID 8619474 . Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (April 1997). "Large-scale concatenation cDNA sequencing" . Genome Research . 7 (4): 353–8. doi :10.1101/gr.7.4.353 . PMC 139146 PMID 9110174 . Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins" . Proceedings of the National Academy of Sciences of the United States of America . 101 (33): 12130–5. Bibcode :2004PNAS..10112130B . doi :10.1073/pnas.0404720101 PMC 514446 PMID 15302935 . Xu L, Blackburn EH (December 2004). "Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules" . The Journal of Cell Biology . 167 (5): 819–30. doi :10.1083/jcb.200408181 . PMC 2172464 PMID 15583028 . Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology . 24 (10): 1285–92. doi :10.1038/nbt1240 . PMID 16964243 . S2CID 14294292 . Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks" . Cell . 127 (3): 635–48. doi :10.1016/j.cell.2006.09.026 PMID 17081983 . S2CID 7827573 . 
