세린/트레오닌-단백질 포스파타아제 2A 56kDa 조절 서브유닛 베타 아이소폼 은 사람에서 PPP2R5B [5] [6] 유전자 에 의해 암호화되는 효소 이다.
기능. 이 유전자의 산물은 포스파타아제 2A 조절 서브유닛 B군에 속합니다. 단백질 포스파타아제 2A는 4대 Ser/Thr 포스파타아제 중 하나로 세포 성장과 분열의 음성 제어에 관여한다. 이것은 다양한 조절 서브유닛과 연관된 촉매 서브유닛과 일정한 조절 서브유닛으로 구성된 공통 이질체 코어 효소로 구성됩니다. B 조절 서브유닛은 기판 선택성과 촉매 활성을 변조할 수 있습니다. 이 유전자는 조절 서브유닛 B56 서브유닛의 [6]
상호 작용 PPP2R5B는 PPP2R1B [7] [7] [8] PPP2CA 와 상호작용하는 것 으로 나타났습니다.
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