PIK3CB
PIK3CB
포스파티딜이노시톨-4,5-이인산 3-키나아제 촉매 서브유닛 베타 이소폼은 PIK3CB [5][6]유전자에 의해 인체 내에서 코드되는 효소이다.
포스포이노시티드 3-키나아제(PI3Ks)는 이노시톨 지질 이노시톨 고리의 3-프라임 OH 위치를 인산화한다.그들은 다양한 승모세포 자극에 반응하여 활성화에 의해 세포 성장을 조절하는 신호 경로의 참가자로 관여되어 왔다.PI3K는 PIK3CB와 같은 110kD 촉매 서브유닛과 85kD 어댑터 서브유닛으로 구성됩니다(Hu 등, 1993).[OMIM [6]제공]
레퍼런스
- ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG000051382 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000032462 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Hu P, Mondino A, Skolnik EY, Schlessinger J (Jan 1994). "Cloning of a novel, ubiquitously expressed human phosphatidylinositol 3-kinase and identification of its binding site on p85". Mol Cell Biol. 13 (12): 7677–88. doi:10.1128/mcb.13.12.7677. PMC 364839. PMID 8246984.
- ^ a b "Entrez Gene: PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide".
추가 정보
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