이 유전자는 인슐린 유사성장인자2(IGF2) 유전자에 대한 안티센스로 발현되며 각인되어 부성 발현된다.추정단백질이 보존되지 않고 번역이 무의미한 매개붕괴(NMD)를 일으킬 것으로 예상되기 때문에 비암호화라고 생각됩니다.이 유전자의 전사는 종양에서 생성되며 세포 성장을 억제하는 기능을 할 수 있습니다.대체 스플라이싱으로 인해 여러 개의 트랜스크립트 변형이 발생합니다.[RefSeq, 2015년 11월 제공]
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Devaney JM, Hoffman EP, Gordish-Dressman H, Kearns A, Zambraski E, Clarkson PM (May 2007). "IGF-II gene region polymorphisms related to exertional muscle damage". J. Appl. Physiol. 102 (5): 1815–23. doi:10.1152/japplphysiol.01165.2006. PMID17289909. S2CID2136915.
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