신장 조직 칼리크레인

Renal tissue kallikrein
티슈칼리크레인
식별자
EC 번호3.4.21.35
CAS 번호.389069-73-2
데이터베이스
인텐츠IntEnz 뷰
브렌다브렌다 입력
엑스퍼시나이스자이메 뷰
케그KEG 입력
메타사이크대사통로
프리암프로필
PDB 구조RCSB PDB PDBe PDBsum

Tissue kallikrein (EC 3.4.21.35, glandular kallikrein, pancreatic kallikrein, submandibular kallikrein, submaxillary kallikrein, kidney kallikrein, urinary kallikrein, kallikrein, salivary kallikrein, kininogenin, kininogenase, callicrein, glumorin, padreatin, padutin, kallidinogenase, bradykininogenase, depot-padutin, urokallikrein, dilminal D, on오크레인 P)는 효소다.[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]이 효소는 다음과 같은 화학 반응을 촉진한다.

작은 분자 기판에 있는 Arg-bond의 우선 분할.키니노겐에서 칼리딘(리실브라디키닌)을 방출하는 고선택적으로 작용한다.

이 효소는 트립신 활성화에 의해 조직 프로칼리크레인으로부터 형성된다.

참고 항목

참조

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  2. ^ Anundi H, Ronne H, Peterson PA, Rask L (December 1982). "Partial amino-acid sequence of the epidermal growth-factor-binding protein". European Journal of Biochemistry. 129 (2): 365–71. doi:10.1111/j.1432-1033.1982.tb07059.x. PMID 6295764.
  3. ^ Pesquero JL, Boschcov P, Oliveira MC, Paiva AC (October 1982). "Effect of substrate size on tonin activity". Biochemical and Biophysical Research Communications. 108 (4): 1441–6. doi:10.1016/s0006-291x(82)80068-5. PMID 6295383.
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  6. ^ Akiyama K, Nakamura T, Iwanaga S, Hara M (December 1987). "The chymotrypsin-like activity of human prostate-specific antigen, gamma-seminoprotein". FEBS Letters. 225 (1–2): 168–72. doi:10.1016/0014-5793(87)81151-1. PMID 3691800.
  7. ^ Evans BA, Drinkwater CC, Richards RI (June 1987). "Mouse glandular kallikrein genes. Structure and partial sequence analysis of the kallikrein gene locus". The Journal of Biological Chemistry. 262 (17): 8027–34. PMID 3036794.
  8. ^ Fiedler F (March 1987). "Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin". European Journal of Biochemistry. 163 (2): 303–12. doi:10.1111/j.1432-1033.1987.tb10801.x. PMID 3643848.
  9. ^ Fujinaga M, James MN (May 1987). "Rat submaxillary gland serine protease, tonin. Structure solution and refinement at 1.8 A resolution". Journal of Molecular Biology. 195 (2): 373–96. doi:10.1016/0022-2836(87)90658-9. PMID 2821276.
  10. ^ Kato H, Nakanishi E, Enjyoji K, Hayashi I, Oh-ishi S, Iwanaga S (December 1987). "Characterization of serine proteinases isolated from rat submaxillary gland: with special reference to the degradation of rat kininogens by these enzymes". Journal of Biochemistry. 102 (6): 1389–404. PMID 3482210.
  11. ^ Bailey GS (1989). "Rat pancreas kallikrein". Methods in Enzymology. 163: 115–28. doi:10.1016/0076-6879(88)63013-8. PMID 3237072.
  12. ^ Blaber M, Isackson PJ, Marsters JC, Burnier JP, Bradshaw RA (September 1989). "Substrate specificities of growth factor associated kallikreins of the mouse submandibular gland". Biochemistry. 28 (19): 7813–9. doi:10.1021/bi00445a043. PMID 2611215.
  13. ^ Chao J, Chao L (1988). "Rat urinary kallikrein". Methods in Enzymology. 163: 128–43. doi:10.1016/0076-6879(88)63014-x. PMID 3070295.
  14. ^ Geiger R, Miska W (1988). "Human tissue kallikrein". Methods in Enzymology. 163: 102–15. doi:10.1016/0076-6879(88)63012-6. PMID 3237071.
  15. ^ Bertrand R, Derancourt J, Kassab R (March 1989). "Selective cleavage at lysine of the 50 kDa-20 kDa connector loop segment of skeletal myosin S-1 by endoproteinase Arg-C". FEBS Letters. 246 (1–2): 171–6. doi:10.1016/0014-5793(89)80277-7. PMID 2523317.
  16. ^ Wines DR, Brady JM, Pritchett DB, Roberts JL, MacDonald RJ (May 1989). "Organization and expression of the rat kallikrein gene family". The Journal of Biological Chemistry. 264 (13): 7653–62. PMID 2708383.
  17. ^ Elmoujahed A, Gutman N, Brillard M, Gauthier F (June 1990). "Substrate specificity of two kallikrein family gene products isolated from the rat submaxillary gland". FEBS Letters. 265 (1–2): 137–40. doi:10.1016/0014-5793(90)80903-v. PMID 2194829.
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