PLA2G2D

PLA2G2D
식별자
별칭	PLA2G2D, PLA2IID, 스플래시, sPLA2-IID, sPLA2S, 인광 효소 A2 그룹 IID
외부 ID	OMIM: 605630 MGI: 1341796 호몰로진: 7892 GeneCard: PLA2G2D
유전자 위치(인간)
쳇.	염색체 1 (인간)
끝	20,195,566 bp
유전자 위치(마우스)
쳇.	4번 염색체(쥐)
끝	138,509,357 bp
RNA 표현 패턴
	표현된 상단
	림프절; ; 맹장; ; 골수 세포; ; 직장의; ; 비장의; ; 담낭; ; 흉선; ; 인두의; ; 흉선; ; 우월한 혀의 표면;
	추가 참조 표현식 데이터
	추가 참조 표현식 데이터
유전자 온톨로지
분자함수	칼슘 이온 결합; 인산염 A2 활성; 헤파린 제본; 금속 이온 결합; 헤파란 황산염 프로테오글리칸 결합; 수산화효소 활동; 인광 결합; 칼슘 의존성 인산화효소 A2 활성;
셀룰러 컴포넌트	세포외 지역;
생물학적 과정	인산 생합성 과정; 아킬 체인 리모델링; 인산염화탄올아민 아킬 체인 리모델링; CD4 양성, CD25 양성, 알파베타 규제 T 셀 차별화; 지질 대사; 인산염리노시톨 아킬 체인 리모델링; 지질 투약 과정; T세포 증식에 대한 부정적인 규제; 인지질글리세롤아킬체인 리모델링; 염증 반응; T세포 활성화에 대한 부정적 규제; 인지질콜린 아킬 체인 리모델링; 인지질 대사 과정; 아라키돈산 분비물;
	출처:아미고 / 퀵고
직교체
	26279
	18782
	ENSG00000117215
	ENSMUSG00000041202
	Q9UNK4
	Q9WVF6
	NM_012400; NM_001271814
	NM_011109; NM_001347230
	NP_001258743; NP_036532
	NP_001334159; NP_035239
	위키다타
인간 보기/편집	마우스 보기/편집

그룹 IID 분비물인산화효소 A2는 인간에서 PLA2G2D 유전자에 의해 암호화된 효소다.^[5]^[6]

참조

^ ^a ^b ^c GRCh38: 앙상블 릴리스 89: ENSG00000117215 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리스 89: ENSMUSG000041202 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishizaki J, Suzuki N, Higashino K, Yokota Y, Ono T, Kawamoto K, Fujii N, Arita H, Hanasaki K (Sep 1999). "Cloning and characterization of novel mouse and human secretory phospholipase A(2)s". J Biol Chem. 274 (35): 24973–9. doi:10.1074/jbc.274.35.24973. PMID 10455175.
^ "Entrez Gene: PLA2G2D phospholipase A2, group IID".

추가 읽기

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Mavoungou E, Georges-Courbot MC, Poaty-Mavoungou V, et al. (1997). "HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes". J. Acquir. Immune Defic. Syndr. Hum. Retrovirol. 16 (1): 1–9. doi:10.1097/00042560-199709010-00001. PMID 9377118.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Shakhov AN, Rubtsov AV, Lyakhov IG, et al. (2001). "SPLASH (PLA2IID), a novel member of phospholipase A2 family, is associated with lymphotoxin deficiency". Genes Immun. 1 (3): 191–9. doi:10.1038/sj.gene.6363659. PMID 11196711.
Lindbom J, Ljungman AG, Lindahl M, Tagesson C (2003). "Increased gene expression of novel cytosolic and secretory phospholipase A(2) types in human airway epithelial cells induced by tumor necrosis factor-alpha and IFN-gamma". J. Interferon Cytokine Res. 22 (9): 947–55. doi:10.1089/10799900260286650. PMID 12396716.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Eckey R, Menschikowski M, Lattke P, Jaross W (2005). "Increased hepatic cholesterol accumulation in transgenic mice overexpressing human secretory phospholipase A2 group IIA". Inflammation. 28 (2): 59–65. doi:10.1023/B:IFLA.0000033021.44105.9c. PMID 15379211. S2CID 21189952.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Takabatake N, Sata M, Inoue S, et al. (2006). "A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease". Am. J. Respir. Crit. Care Med. 172 (9): 1097–104. doi:10.1164/rccm.200503-319OC. PMID 16002569.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Lindbom J, Ljungman AG, Tagesson C (2007). "Interferon gamma-induced gene expression of the novel secretory phospholipase A2 type IID in human monocyte-derived macrophages is inhibited by lipopolysaccharide". Inflammation. 29 (2–3): 108–117. doi:10.1007/s10753-006-9007-x. PMID 16897354. S2CID 22943118.

인간 염색체 1번 유전자에 관한 이 기사는 단조롭다.위키피디아를 확장하여 도울 수 있다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리스 89: ENSG00000117215 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리스 89: ENSMUSG000041202 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10455175-5] Ishizaki J, Suzuki N, Higashino K, Yokota Y, Ono T, Kawamoto K, Fujii N, Arita H, Hanasaki K (Sep 1999). "Cloning and characterization of novel mouse and human secretory phospholipase A(2)s". J Biol Chem. 274 (35): 24973–9. doi:10.1074/jbc.274.35.24973. PMID 10455175.

[entrez-6] "Entrez Gene: PLA2G2D phospholipase A2, group IID".

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PLA2G2D

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